HegeLab.org

Papers
Talks
Posters

Papers

  1. Gyimesi, G., Ramachandran, S., Kota, P., Dokholyan, N.V., Sarkadi, B., Hegedus, T., ATP hydrolysis at one of the two sites in ABC transporters initiates transport related conformational transitions. BBA Biomembranes 2011, accepted for publication;
  2. Brozik, A., Hegedus, C., Erdei, Z., Hegedus, T., Ozvegy-Laczka, C., Szakacs, G., Sarkadi, B., Tyrosine kinase inhibitors as modulators of ATP binding cassette multidrug transporters: substrates, chemosensitizers or inducers of acquired multidrug resistance? Expert Opin Drug Metab Toxicol. 2011, 7:623-42 PubMed

Talks

  1. Hegedus, T., Telbisz, A., Sarkadi, B, Purification of functional ABC transporters for structural studies, Locher-Lab, ETH, Zurich, Switzerland, March, 2011;
  2. Hegedus, T., The role of F508 in the domain folding and in the domain-domain assembly of CFTR, Department of Biophysics, University of Debrecen, Debrecen, Hungary, November, 2010;
  3. Hegedus, T., Structure and dynamics of ABC proteins: interplay of computation and Experiments, Department of Biochemistry, University of Oxford, Oxford, UK, October, 2010;
  4. Gyimesi, G., Ramachandran, S., Kota, P., Dokholyan, N.V., Sarkadi B., Hegedus, T., Computational Study of the Long Scale Dynamics of ABC Proteins. 7th North American ABC meeting, NCI-Frederick, Frederick, MD, USA, September, 2010;
  5. Tordai, H., Ozvegy-Laczka, C., Tusnady, E.G., Aleksandrov, L., Riordan, J.R., Sarkadi, B., Hegedus T., Investigation of membrane topology of ABC proteins using computational and experimental methods, Membrane Transport Conference, Sumeg, Hungary, May of 2010 (oral presentation selected from posters).
Posters
  1. Tordai, H., Ozvegy-Laczka, C., Tusnady, E.G., Aleksandrov, L., Riordan, J.R., Sarkadi, B, Hegedus T., Investigation of membrane topology of ABC proteins using computational and experimental methods, Membrane Transport Conference, Sumeg, Hungary, May of 2010;
  2. Gyimesi, G., Ramachandran, S., Kota, P., Dokholyan, N.V., Sarkadi, B., Hegedus, T., Characterizing the dynamics of different conformers of ABC transporters. Membrane Transport Conference, Sumeg, Hungary, May of 2010;
  3. Gyimesi, G., Ramachandran, S., Kota, P., Dokholyan, N.V., Sarkadi, B., Hegedus, T., Characterizing the dynamics of different conformers of ABC transporters. ATP-Binding Cassette (ABC) Proteins: From Multidrug Resistance to Genetic Disease, Innsbruck, Austria, 2010 (in the 15 best posters out of ~200).