Papers
Talks
Posters
Papers
- Gyimesi, G., Ramachandran, S., Kota, P., Dokholyan, N.V., Sarkadi, B., Hegedus, T., ATP hydrolysis at one of the two sites in ABC transporters initiates transport related conformational transitions. BBA Biomembranes 2011, accepted for publication;
- Brozik, A., Hegedus, C., Erdei, Z., Hegedus, T., Ozvegy-Laczka, C., Szakacs, G., Sarkadi, B., Tyrosine kinase inhibitors as modulators of ATP binding cassette multidrug transporters: substrates, chemosensitizers or inducers of acquired multidrug resistance? Expert Opin Drug Metab Toxicol. 2011, 7:623-42 PubMed
Talks
- Hegedus, T., Telbisz, A., Sarkadi, B, Purification of functional ABC transporters for structural studies, Locher-Lab, ETH, Zurich, Switzerland, March, 2011;
- Hegedus, T., The role of F508 in the domain folding and in the domain-domain assembly of CFTR, Department of Biophysics, University of Debrecen, Debrecen, Hungary, November, 2010;
- Hegedus, T., Structure and dynamics of ABC proteins: interplay of computation and Experiments, Department of Biochemistry, University of Oxford, Oxford, UK, October, 2010;
- Gyimesi, G., Ramachandran, S., Kota, P., Dokholyan, N.V., Sarkadi B., Hegedus, T., Computational Study of the Long Scale Dynamics of ABC Proteins. 7th North American ABC meeting, NCI-Frederick, Frederick, MD, USA, September, 2010;
- Tordai, H., Ozvegy-Laczka, C., Tusnady, E.G., Aleksandrov, L., Riordan, J.R., Sarkadi, B., Hegedus T., Investigation of membrane topology of ABC proteins using computational and experimental methods, Membrane Transport Conference, Sumeg, Hungary, May of 2010 (oral presentation selected from posters).
Posters
- Tordai, H., Ozvegy-Laczka, C., Tusnady, E.G., Aleksandrov, L., Riordan, J.R., Sarkadi, B, Hegedus T., Investigation of membrane topology of ABC proteins using computational and experimental methods, Membrane Transport Conference, Sumeg, Hungary, May of 2010;
- Gyimesi, G., Ramachandran, S., Kota, P., Dokholyan, N.V., Sarkadi, B., Hegedus, T., Characterizing the dynamics of different conformers of ABC transporters. Membrane Transport Conference, Sumeg, Hungary, May of 2010;
- Gyimesi, G., Ramachandran, S., Kota, P., Dokholyan, N.V., Sarkadi, B., Hegedus, T., Characterizing the dynamics of different conformers of ABC transporters. ATP-Binding Cassette (ABC) Proteins: From Multidrug Resistance to Genetic Disease, Innsbruck, Austria, 2010 (in the 15 best posters out of ~200).