Publications - Tordai, Hedvig

2025

  1. Int J Mol Sci. 2025 Jul 21;26(14):7004. doi: 10.3390/ijms26147004. [DOI: 10.3390/ijms26147004] [PMID: 40725251]
    Titin's Intrinsically Disordered PEVK Domain Modulates Actin Polymerization.
    Altorjay AG, Tordai H, Zolcsak A, Kosa N, Hegedus T, Kellermayer M

2024

  1. Sci Data. 2024 May 14;11(1):495. [DOI: 10.1038/s41597-024-03327-8] [PMID: 38744964]
    Analysis of AlphaMissense data in different protein groups and structural context.
    Tordai H, Torres O, Csepi M, Padanyi R, Lukacs GL, Hegedus T
  2. Sci Rep. 2024 Sep 11;14(1):21200. doi: 10.1038/s41598-024-71144-5. [DOI: 10.1038/s41598-024-71144-5] [PMID: 39261533]
    SARS-CoV-2 envelope protein alters calcium signaling via SERCA interactions.
    Berta B, Tordai H, Lukacs GL, Papp B, Enyedi A, Padanyi R, Hegedus T

2022

  1. Comput Struct Biotechnol J. 2022 May 23;20:2587-2599. [DOI: 10.1016/j.csbj.2022.05.036] [PMID: 35685375]
    Nanomechanics combined with HDX reveals allosteric drug binding sites of CFTR NBD1.
    Padanyi R, Farkas B, Tordai H, Kiss B, Grubmuller H, Soya N, Lukacs GL, Kellermayer M, Hegedus T
  2. Int J Mol Sci. 2022 Aug 9;23(16):8877. [DOI: 10.3390/ijms23168877] [PMID: 36012140]
    Comprehensive Collection and Prediction of ABC Transmembrane Protein Structures in the AI Era of Structural Biology.
    Tordai H, Suhajda E, Sillitoe I, Nair S, Varadi M, Hegedus T

2021

  1. Nucleic Acids Res. 2021 Jan 8;49(D1):D355-D360. [DOI: 10.1093/nar/gkaa954] [PMID: 33119751]
    The MemMoRF database for recognizing disordered protein regions interacting with cellular membranes.
    Csizmadia G, Erdos G, Tordai H, Padanyi R, Tosatto S, Dosztanyi Z, Hegedus T
  2. Cell Mol Life Sci. 2021 Mar;78(5):2329-2339. [DOI: 10.1007/s00018-020-03651-3] [PMID: 32979053]
    The transport pathway in the ABCG2 protein and its regulation revealed by molecular dynamics simulations.
    Nagy T, Toth A, Telbisz A, Sarkadi B, Tordai H, Tordai A, Hegedus T

2020

  1. Cell Mol Life Sci. 2020 Feb;77(4):765-778. [DOI: 10.1007/s00018-019-03211-4] [PMID: 31327045]
    Discovering the chloride pathway in the CFTR channel.
    Farkas B, Tordai H, Padanyi R, Tordai A, Gera J, Paragi G, Hegedus T

2018

  1. Comput Struct Biotechnol J. 2018 Oct 18;16:396-403. [DOI: 10.1016/j.csbj.2018.10.008] [PMID: 30425800]
    Quantitative comparison of ABC membrane protein type I exporter structures in a standardized way.
    Csizmadia G, Farkas B, Spagina Z, Tordai H, Hegedus T

2017

  1. Biochem Biophys Res Commun. 2017 Sep 30;491(4):986-993. [DOI: 10.1016/j.bbrc.2017.07.165] [PMID: 28774558]
    Molecular dynamics of the cryo-EM CFTR structure.
    Tordai H, Leveles I, Hegedus T
  2. Database (Oxford). 2017 Jan 1;2017(1):bax023. [DOI: 10.1093/database/bax023] [PMID: 28365738]
    ABCMdb reloaded: updates on mutations in ATP binding cassette proteins.
    Tordai H, Jakab K, Gyimesi G, Andras K, Brozik A, Sarkadi B, Hegedus T

2013

  1. Biochem Biophys Res Commun. 2013 Jul 19;437(1):140-5. [DOI: 10.1016/j.bbrc.2013.06.054] [PMID: 23800412]
    Effects of the gout-causing Q141K polymorphism and a CFTR DeltaF508 mimicking mutation on the processing and stability of the ABCG2 protein.
    Saranko H, Tordai H, Telbisz A, Ozvegy-Laczka C, Erdos G, Sarkadi B, Hegedus T

2012

  1. Hum Mutat. 2012 Nov;33(11):1547-56. [DOI: 10.1002/humu.22138] [PMID: 22693078]
    ABCMdb: a database for the comparative analysis of protein mutations in ABC transporters, and a potential framework for a general application.
    Gyimesi G, Borsodi D, Saranko H, Tordai H, Sarkadi B, Hegedus T